ATHN 1: A Cross-Sectional Analysis of Cardiovascular Disease in the Hemophilia Population

Status: Closed
Principal Investigator: Barbara A. Konkle, MD, Bloodworks Northwest
Sponsor: Centers for Disease Control and Prevention

Now completed, ATHN 1 was a cross-sectional observational study aimed at understanding whether men with hemophilia are protected from cardiovascular disease (CVD). Using the ATHNdataset and study-specific data, the study looked to identify the risk factors and prevalence of CVD in older men with hemophilia A and B and compare this data to the general population.

The ATHN 1 study showed that older men with moderate to severe hemophilia commonly report risk factors for CVD. Despite this finding, the prevalence of reported CVD is low (9.7%), which suggests that men with hemophilia may be protected from forming disease-causing blood clots.

Another finding suggests that older men with hemophilia may be at greater risk of kidney disease. The ATHN 1 extension looked to determine the risk factors and prevalence of kidney disease among the study participants.

To learn more about the study findings of ATHN 1, see the ATHN CV.

The American Thrombosis and Hemostasis Network (ATHN) is a nonprofit organization committed to advancing and improving care for individuals affected by bleeding and thrombotic disorders. ATHN manages a national database of patient health data that can be used to improve care and support vital research.