ATHN 2: A Longitudinal, Observational Study of Previously Treated Patients (PTPs) Switching Factor Replacement Products

Status: Closed
Principal Investigator: Ellis Neufeld, MD, PhD, St. Jude Children&rsquo;s Research Hospital
Sponsor: ATHN

There are nearly a dozen factor replacement products available today. To better understand the effects of switching to any of these factor products, ATHN sponsored ATHN 2: Factor Switching Study, a research study on the effects of switching factor products. The ATHN 2 project ran from 2015 to 2019.

Unlike manufacturer-sponsored studies of individual factor products, ATHN 2 was designed to study all of the new factor products over a period of many years, after they had been approved by the U.S. Food and Drug Administration (FDA). Patients who had a prior history of inhibitors to factors (but were free of an inhibitor at the time of the study) were eligible to participate.

To learn more about how the study was conducted, download the ATHN 2 Study Brochure.

The American Thrombosis and Hemostasis Network (ATHN) is a nonprofit organization committed to advancing and improving care for individuals affected by bleeding and thrombotic disorders. ATHN manages a national database of patient health data that can be used to improve care and support vital research.